QSOX1

Across TCGA patient cohorts, QSOX1 mutation is significantly associated with the RNA expression of many other genes, with 5,024 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible QSOX1-associated genes across cancer lineages are DNM1P28, BAK1P2, and RPL21P10. Each is linked with QSOX1 in more than 2 cancer types. Because this analysis shows association rather than direction, both QSOX1-to-partner and partner-to-QSOX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNM1P28 grouped by QSOX1-low versus QSOX1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (QSOX1→partner) and Y-score (partner→QSOX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	DNM1P28 →	+0.159	+4.373	<.001	.001	3	3
SKCM	BAK1P2 →	+0.055	+2.395	.001	<.001	3	2
SKCM	RPL21P10 →	+0.215	+3.604	.007	.001	3	2
SKCM	SCG5-AS1 →	+0.156	+3.351	.006	.006	3	2
UCEC	DCP1A →	+0.396	+1.688	.002	.001	3	2
UCEC	CWC25 →	+0.315	+2.445	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,024 associations by consensus.

DNM1P28 by QSOX1 expression — BLCA

Explore this box plot interactively →