QDPR

Across TCGA patient cohorts, QDPR RNA expression is significantly associated with the protein abundance of many other proteins, with 17,500 significant associations in total. GBM shows the largest number of these associations.

The most reproducible QDPR-associated proteins across cancer lineages are STK38, CTBP1, and HTT. Each is linked with QDPR in more than 4 cancer types. Because this analysis shows association rather than direction, both QDPR-to-partner and partner-to-QDPR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, QDPR versus STK38 in GBM, with a Pearson correlation of -0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (QDPR→partner) and Y-score (partner→QDPR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	STK38 →	-0.213	-0.549	<.001	<.001	3	5
OV	CTBP1 →	+0.257	+0.455	<.001	<.001	3	4
OV	HTT →	+0.381	+0.541	<.001	<.001	3	4
OV	LRPAP1 →	+0.294	+0.491	<.001	<.001	3	4
GBM	RPL3 →	-0.264	-0.630	<.001	<.001	3	4
GBM	RPS8 →	-0.322	-0.649	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,500 associations by consensus.

QDPR vs STK38 — GBM

Explore this scatter interactively →