QDPR

Across TCGA pan-cancer cohorts, QDPR RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated QDPR data layer compared with 2 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher QDPR RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated QDPR expression acts as an unfavorable survival marker, although some lineages such as KIRP and KIRC show a favorable association.

KIRP, UVM, and KIRC are the cancer types where QDPR RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Quartile	All	0.897	0.418	<.001	78	view →
UVM	DFS	Median	All	0.428	0.733	<.001	76	view →
KIRC	OS	Median	All	0.718	0.534	<.001	62	view →
KICH	DFS	Quartile	All	0.658	1.000	.004	47	view →
BRCA	OS	Tertile	All	0.951	0.898	.005	44	view →
LIHC	OS	Tertile	All	0.756	0.494	.001	29	view →
UCS	DFS	Quartile	III,IV	0.645	0.106	.008	24	view →
READ	DFS	Quartile	II,III,IV	0.900	0.237	.004	23	view →
UCEC	OS	Tertile	III,IV	0.708	0.441	.007	18	view →
PAAD	DFS	Quartile	All	0.486	0.191	.010	16	view →
PRAD	DFS	Quartile	All	0.958	0.892	.006	14	view →
COAD	DFS	Quartile	II,III,IV	0.607	0.855	.011	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

QDPR–KIRP (DFS)

Open the KIRP breakdown →