PZP

Across TCGA patient cohorts, PZP RNA expression is significantly associated with the protein abundance of many other proteins, with 18,898 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PZP-associated proteins across cancer lineages are ARHGAP45_S578, THEMIS, and EVL. Each is linked with PZP in more than 6 cancer types. Because this analysis shows association rather than direction, both PZP-to-partner and partner-to-PZP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PZP versus ARHGAP45_S578 in LSCC, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PZP→partner) and Y-score (partner→PZP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARHGAP45_S578 →	+0.946	+0.906	<.001	<.001	3	7
UCEC	THEMIS →	+0.591	+1.018	.005	.009	3	7
HNSC	EVL →	+0.655	+1.097	<.001	<.001	3	7
HNSC	GIMAP4 →	+0.598	+0.914	<.001	<.001	3	7
LSCC	GRAP2 →	+0.675	+1.097	<.001	<.001	3	7
OV	ARHGEF6_S684 →	+0.884	+0.345	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,898 associations by consensus.

PZP vs ARHGAP45_S578 — LSCC

Explore this scatter interactively →