PYDC1

Across TCGA patient cohorts, PYDC1 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PYDC1-associated genes across cancer lineages are RN7SL248P, MRPS18CP4, and RNU6-374P. Each is linked with PYDC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PYDC1-to-partner and partner-to-PYDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by PYDC1-low versus PYDC1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PYDC1→partner) and Y-score (partner→PYDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.125	+4.400	<.001	.006	3	3
BLCA	MRPS18CP4 →	+0.559	+4.680	<.001	.003	3	1
LUAD	RNU6-374P →	+0.392	+7.930	<.001	.008	3	1
LUAD	LINC00709 →	+0.079	+7.930	<.001	.008	3	1
UCEC	RPL23AP86 →	+0.251	+3.738	.005	.006	3	1
UCEC	MIR3928 →	+0.673	+3.386	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

RN7SL248P by PYDC1 expression — UCEC

Explore this box plot interactively →