PXN-AS1

Across TCGA patient cohorts, PXN-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,167 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PXN-AS1-associated proteins across cancer lineages are WDR5, RBM12, and SART3. Each is linked with PXN-AS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PXN-AS1-to-partner and partner-to-PXN-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PXN-AS1 versus WDR5 in GBM, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PXN-AS1→partner) and Y-score (partner→PXN-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	WDR5 →	+0.322	+0.310	<.001	<.001	3	7
GBM	RBM12 →	+0.271	+0.339	<.001	<.001	3	7
GBM	SART3 →	+0.234	+0.347	<.001	<.001	3	6
GBM	GTF3C4 →	+0.318	+0.286	<.001	<.001	3	6
GBM	SMC3 →	+0.286	+0.303	<.001	<.001	3	6
HNSC	PPP1CC →	+0.242	+0.346	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,167 associations by consensus.

PXN-AS1 vs WDR5 — GBM

Explore this scatter interactively →