PXDNL

Across TCGA patient cohorts, PXDNL RNA expression is significantly associated with the protein abundance of many other proteins, with 8,088 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PXDNL-associated proteins across cancer lineages are ANGPT2, HIP1, and SPARC. Each is linked with PXDNL in more than 3 cancer types. Because this analysis shows association rather than direction, both PXDNL-to-partner and partner-to-PXDNL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PXDNL versus ANGPT2 in PDAC, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PXDNL→partner) and Y-score (partner→PXDNL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	ANGPT2 →	+0.841	+0.541	.003	<.001	3	4
GBM	HIP1 →	+0.287	+0.536	.002	.001	3	4
OV	SPARC →	+0.595	+0.395	.001	<.001	3	4
CCRCC	COL5A3 →	+0.585	+0.541	<.001	<.001	3	4
PDAC	DCHS1 →	+0.347	+0.361	<.001	<.001	3	4
PDAC	RCN3 →	+0.590	+0.504	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,088 associations by consensus.

PXDNL vs ANGPT2 — PDAC

Explore this scatter interactively →