PWRN2

Across TCGA patient cohorts, PWRN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,947 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PWRN2-associated proteins across cancer lineages are PRKAR2B, UTP4, and QDPR. Each is linked with PWRN2 in more than 3 cancer types. Because this analysis shows association rather than direction, both PWRN2-to-partner and partner-to-PWRN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PWRN2 versus PRKAR2B in GBM, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PWRN2→partner) and Y-score (partner→PWRN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRKAR2B →	+0.735	+0.239	<.001	<.001	3	4
PDAC	UTP4 →	-0.320	-0.649	<.001	<.001	3	3
GBM	QDPR →	+0.399	+0.268	<.001	.002	3	3
COAD	PREPL →	+0.290	+0.005	.001	.004	3	3
UCEC	HIC1_S313 →	+0.468	+0.488	.001	.001	3	3
UCEC	HSPB6 →	+0.667	+0.538	.003	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,947 associations by consensus.

PWRN2 vs PRKAR2B — GBM

Explore this scatter interactively →