PWP2

Across TCGA patient cohorts, PWP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 5,030 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PWP2-associated proteins across cancer lineages are MRTO4, WDR43, and ELAPOR1_S960. Each is linked with PWP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PWP2-to-partner and partner-to-PWP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PWP2 versus MRTO4 in BRCA, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PWP2→partner) and Y-score (partner→PWP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MRTO4 →	+0.379	+0.725	<.001	<.001	3	3
BRCA	WDR43 →	+0.330	+0.572	<.001	.004	3	2
LUAD	ELAPOR1_S960 →	+1.075	+0.813	.004	.004	3	2
HNSC	KRT8_S410 →	-1.523	-1.248	.003	.007	3	2
OV	TJAP1_T547 →	-0.809	-0.657	.005	.008	3	2
OV	OSBPL11_T27 →	+0.577	+0.906	.005	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,030 associations by consensus.

PWP2 vs MRTO4 — BRCA

Explore this scatter interactively →