PVR

Across TCGA patient cohorts, PVR RNA expression is significantly associated with the protein abundance of many other proteins, with 13,702 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PVR-associated proteins across cancer lineages are UTP4, WDR43, and UTP15. Each is linked with PVR in more than 6 cancer types. Because this analysis shows association rather than direction, both PVR-to-partner and partner-to-PVR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PVR versus UTP4 in BRCA, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PVR→partner) and Y-score (partner→PVR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	UTP4 →	+0.373	+0.506	<.001	<.001	3	7
BRCA	WDR43 →	+0.298	+0.658	<.001	<.001	3	6
COAD	UTP15 →	+0.307	+0.487	<.001	.003	2	6
UCEC	UTP18 →	+0.251	+0.593	<.001	.001	3	5
BRCA	PLOD1 →	+0.535	+0.803	<.001	<.001	3	5
BRCA	PLOD3 →	+0.470	+0.551	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,702 associations by consensus.

PVR vs UTP4 — BRCA

Explore this scatter interactively →