PTPN14

Across TCGA patient cohorts, PTPN14 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,422 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTPN14-associated proteins across cancer lineages are PTPN14_S314, PTPN14_S594, and PTPN14_S578. Each is linked with PTPN14 in more than 8 cancer types. Because this analysis shows association rather than direction, both PTPN14-to-partner and partner-to-PTPN14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTPN14 versus PTPN14_S314 in OV, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPN14→partner) and Y-score (partner→PTPN14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PTPN14_S314 →	+0.444	+1.019	<.001	<.001	3	9
LSCC	PTPN14_S594 →	+0.950	+0.945	<.001	<.001	3	8
LSCC	PTPN14_S578 →	+0.791	+0.955	<.001	<.001	3	7
UCEC	PTPN14_S620 →	+0.828	+0.509	.001	.001	3	7
LSCC	PTPN14_S760 →	+1.033	+0.972	<.001	<.001	3	7
HNSC	PTPN14_S809 →	+0.817	+1.095	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,422 associations by consensus.

PTPN14 vs PTPN14_S314 — OV

Explore this scatter interactively →