PTPA

Across TCGA patient cohorts, PTPA RNA expression is significantly associated with the RNA expression of many other genes, with 19,113 significant associations in total. ACC shows the largest number of these associations.

The most reproducible PTPA-associated genes across cancer lineages are FBXW5, MAN1B1, and SPOUT1. Each is linked with PTPA in more than 32 cancer types. Because this analysis shows association rather than direction, both PTPA-to-partner and partner-to-PTPA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTPA versus FBXW5 in ACC, with a Pearson correlation of 0.87.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPA→partner) and Y-score (partner→PTPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	FBXW5 →	+1.253	+1.155	<.001	<.001	3	33
ACC	MAN1B1 →	+1.373	+1.120	<.001	<.001	3	33
ACC	SPOUT1 →	+1.123	+1.190	<.001	<.001	3	33
ACC	TRAF2 →	+1.146	+0.983	<.001	<.001	3	32
ACC	TOR1A →	+1.154	+1.209	<.001	<.001	3	32
ACC	SURF4 →	+1.279	+1.058	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,113 associations by consensus.

PTPA vs FBXW5 — ACC

Explore this scatter interactively →