Across TCGA patient cohorts, PTP4A2 mutation is significantly associated with the RNA expression of many other genes, with 271 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PTP4A2-associated genes across cancer lineages are MIR6129, LINC02745, and LINC00273. Each is linked with PTP4A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PTP4A2-to-partner and partner-to-PTP4A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTP4A2→partner) and Y-score (partner→PTP4A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6129 →	+0.477	+2.496	<.001	.004	3	1
BLCA	LINC02745 →	+0.034	+4.562	.009	.006	3	1
BLCA	LINC00273 →	+0.012	+4.433	.008	.007	3	1
BLCA	LINC02258 →	+0.031	+4.433	.009	.007	3	1
BLCA	MIR4300 →	+0.159	+5.722	<.001	.001	3	1
BLCA	GTF3C6P3 →	+0.157	+3.937	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 271 associations by consensus.

Exploration

PTP4A2 survival (RNA) · tumor vs normal (RNA) · all PTP4A2 data types