PTMA

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PTMA RNA expression is significantly associated with the protein abundance of many other proteins, with 13,366 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTMA-associated proteins across cancer lineages are CDK1, MCM2, and MCM4. Each is linked with PTMA in more than 6 cancer types. Because this analysis shows association rather than direction, both PTMA-to-partner and partner-to-PTMA results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PTMA→partner) and Y-score (partner→PTMA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCDK1 →+0.630+0.581<.001<.00137
OVMCM2 →+0.725+0.560<.001<.00137
OVMCM4 →+0.799+0.502<.001.00137
OVMCM5 →+0.724+0.646<.001<.00137
OVMCM6 →+0.785+0.633<.001<.00137
OVMCM7 →+0.817+0.636<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,366 associations by consensus.

Exploration