PTGER4

Across TCGA patient cohorts, PTGER4 mutation is significantly associated with the RNA expression of many other genes, with 3,642 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PTGER4-associated genes across cancer lineages are RNA5SP412, LINC02559, and GPC6-AS1. Each is linked with PTGER4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PTGER4-to-partner and partner-to-PTGER4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by PTGER4-low versus PTGER4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGER4→partner) and Y-score (partner→PTGER4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.467	+1.782	<.001	.001	3	2
CESC	LINC02559 →	+1.329	+5.342	<.001	.002	3	2
CESC	GPC6-AS1 →	+0.093	+4.539	<.001	.008	3	2
CESC	RN7SL134P →	+0.208	+4.874	<.001	.002	3	2
UCEC	INSL4 →	+0.419	+1.753	.003	<.001	3	2
HNSC	RNU7-61P →	+0.576	+4.425	.006	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,642 associations by consensus.

RNA5SP412 by PTGER4 expression — UCEC

Explore this box plot interactively →