PTGDR

Across TCGA cell cohorts, PTGDR RNA expression is significantly associated with the go_rna of many other GO terms, with 173 significant associations in total. CNS shows the largest number of these associations.

The most reproducible PTGDR-associated GO terms across cancer lineages are Positive regulation of intracellular transport, Response to acid chemical, and Protein folding in endoplasmic reticulum. Each is linked with PTGDR in more than 4 cancer types. Because this analysis shows association rather than direction, both PTGDR-to-partner and partner-to-PTGDR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular transport grouped by PTGDR-low versus PTGDR-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGDR→partner) and Y-score (partner→PTGDR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Positive regulation of intracellular transport →	+0.054	+0.053	<.001	.005	3	5
CNS	Response to acid chemical →	+0.028	+0.036	.005	.009	3	3
SOFT_TISSUE	Protein folding in endoplasmic reticulum →	+0.102	+0.035	<.001	.008	3	3
CNS	Negative regulation of protein catabolic process →	+0.037	+0.039	<.001	.004	3	3
CNS	Endothelial cell migration →	+0.058	+0.038	.003	.005	3	3
CNS	Cotranslational protein targeting to membrane →	+0.074	+0.053	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 173 associations by consensus.

Positive regulation of intracellular transport by PTGDR expression — CNS

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