PTGDR

Across TCGA pan-cancer cohorts, PTGDR RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated PTGDR data layer compared with 3 for mutation status.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher PTGDR RNA is associated with better overall survival. In most high-consensus cancer types, elevated PTGDR expression acts as an unfavorable survival marker, although some lineages such as SKCM and UCEC show a favorable association.

SKCM, UCEC, and KIRP are the cancer types where PTGDR RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	All	0.408	0.275	<.001	112	view →
UCEC	OS	Quartile	II,III,IV	0.807	0.436	.001	64	view →
KIRP	DFS	Tertile	All	0.362	0.842	.002	50	view →
ACC	DFS	Median	All	0.738	0.431	.001	36	view →
LIHC	OS	Quartile	III,IV	0.788	0.343	.001	33	view →
UVM	DFS	Quartile	All	0.366	0.738	.003	32	view →
HNSC	DFS	Quartile	IV	0.739	0.494	.003	30	view →
LUSC	OS	Tertile	II,III,IV	0.309	0.508	.004	27	view →
UCS	DFS	Median	IV	0.909	0.416	.008	20	view →
LUAD	OS	Quartile	All	0.749	0.592	.001	19	view →
KIRC	OS	Quartile	All	0.516	0.719	.010	17	view →
THCA	DFS	Median	IV	0.884	0.459	.002	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

PTGDR–SKCM (OS)

Open the SKCM breakdown →