PTENP1-AS

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PTENP1-AS mutation is significantly associated with the RNA expression of many other genes, with 3,812 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PTENP1-AS-associated genes across cancer lineages are RN7SL861P, ADAM20P2, and RNA5SP66. Each is linked with PTENP1-AS in more than 1 cancer types. Because this analysis shows association rather than direction, both PTENP1-AS-to-partner and partner-to-PTENP1-AS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL861P grouped by PTENP1-AS-low versus PTENP1-AS-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTENP1-AS→partner) and Y-score (partner→PTENP1-AS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCRN7SL861P →+0.164+3.847<.001.00632
HNSCADAM20P2 →+0.050+4.526<.001.00732
STADRNA5SP66 →+0.547+4.879<.001.00232
LUSCMIR5571 →+0.361+4.882<.001.00532
SKCMRNU1-19P →+0.374+5.682<.001<.00132
COADRNU6-130P →+1.033+3.758.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,812 associations by consensus.

RN7SL861P by PTENP1-AS expression — HNSC

Box plot of RN7SL861P in PTENP1-AS-low vs PTENP1-AS-high samples in HNSC.

Explore this box plot interactively →

Exploration