PTENP1-AS

Across TCGA pan-cancer cohorts, PTENP1-AS RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of PTENP1-AS’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where PTENP1-AS RNA is repressed in tumor relative to normal tissue. In most cancer types PTENP1-AS is over-expressed in tumor, although a few such as BRCA and STAD show the opposite, repressed pattern.

BRCA, STAD, and COAD are the cancer types where PTENP1-AS tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PTENP1-AS RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	All	−0.544	<.001	6	view →
STAD	Male	All	−0.303	<.001	6	view →
COAD	All	II,III,IV	−0.201	<.001	6	view →
KICH	All	II,III,IV	−0.103	.025	4	view →
READ	All	All	−0.563	.003	3	view →
LUAD	Female	II,III,IV	−0.244	<.001	3	view →
ESCA	All	II,III,IV	−0.734	.013	2	view →
BLCA	All	IV	−0.402	.004	2	view →
LUSC	Female	III,IV	−0.400	.002	2	view →
UCEC	All	All	−0.252	.014	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

PTENP1-AS–BRCA

Open the BRCA breakdown →