PTENP1-AS

Across TCGA pan-cancer cohorts, PTENP1-AS RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated PTENP1-AS data layer compared with 4 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher PTENP1-AS RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PTENP1-AS expression acts as an unfavorable survival marker, although some lineages such as UCS and LUAD show a favorable association.

COAD, BLCA, and UCS are the cancer types where PTENP1-AS RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	0.683	0.804	.007	54	view →
BLCA	OS	Quartile	II,III,IV	0.313	0.475	.009	53	view →
UCS	DFS	Quartile	II,III,IV	0.685	0.143	.005	42	view →
LUAD	OS	Quartile	All	0.910	0.789	.003	36	view →
READ	OS	Quartile	All	0.800	0.939	.004	34	view →
HNSC	DFS	Tertile	All	0.536	0.652	.003	33	view →
BRCA	OS	Median	All	0.943	0.904	.005	19	view →
GBM	DFS	Median	All	0.367	0.187	.011	9	view →
SARC	DFS	Median	All	0.676	0.541	.006	9	view →
THYM	DFS	Median	II,III,IV	0.756	0.958	.020	8	view →
LUSC	OS	Median	II,III,IV	0.675	0.353	.006	8	view →
PAAD	DFS	Quartile	All	0.486	0.233	.006	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

PTENP1-AS–COAD (DFS)

Open the COAD breakdown →