PTENP1-AS

Across TCGA patient cohorts, PTENP1-AS mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PTENP1-AS-associated genes across cancer lineages are ASNS, Tuberin, and C-Raf. Each is linked with PTENP1-AS in more than 2 cancer types. Because this analysis shows association rather than direction, both PTENP1-AS-to-partner and partner-to-PTENP1-AS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by PTENP1-AS-low versus PTENP1-AS-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTENP1-AS→partner) and Y-score (partner→PTENP1-AS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.434	+2.222	.001	.010	3	3
UCEC	Tuberin →	+0.311	+2.125	.002	.010	3	2
UCEC	C-Raf →	+0.187	+1.678	<.001	.023	3	2
UCEC	eEF2 →	+0.420	+2.321	.002	.033	3	1
UCEC	FoxM1 →	+0.253	+2.584	.010	.001	3	1
UCEC	GATA6 →	-0.155	-1.577	.010	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

ASNS by PTENP1-AS expression — UCEC

Explore this box plot interactively →