PTCD3

Across TCGA patient cohorts, PTCD3 mutation is significantly associated with the RNA expression of many other genes, with 3,329 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PTCD3-associated genes across cancer lineages are RN7SL248P, RN7SKP221, and USP9YP10. Each is linked with PTCD3 in more than 2 cancer types. Because this analysis shows association rather than direction, both PTCD3-to-partner and partner-to-PTCD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by PTCD3-low versus PTCD3-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTCD3→partner) and Y-score (partner→PTCD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL248P →	+0.212	+7.584	<.001	<.001	3	3
BRCA	RN7SKP221 →	+0.099	+8.471	<.001	.005	3	2
LGG	USP9YP10 →	+0.049	+7.977	<.001	.007	3	2
READ	BPNT2P →	+0.148	+6.681	<.001	<.001	3	2
HNSC	HMGB3P2 →	+0.114	+4.221	.004	.009	3	2
HNSC	YPEL5P1 →	+0.082	+5.339	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,329 associations by consensus.

RN7SL248P by PTCD3 expression — CESC

Explore this box plot interactively →