PTAFR

Across TCGA cell cohorts, PTAFR RNA expression is significantly associated with the go_rna of many other GO terms, with 4,987 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PTAFR-associated GO terms across cancer lineages are Small GTPase-mediated signal transduction, Regulation of hippocampal neuron apoptotic process, and Negative regulation of supramolecular fiber organization. Each is linked with PTAFR in more than 10 cancer types. Because this analysis shows association rather than direction, both PTAFR-to-partner and partner-to-PTAFR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Small GTPase-mediated signal transduction grouped by PTAFR-low versus PTAFR-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTAFR→partner) and Y-score (partner→PTAFR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Small GTPase-mediated signal transduction →	+0.074	+1.754	.002	<.001	3	11
URINARY_TRACT	Regulation of hippocampal neuron apoptotic process →	+1.776	+1.881	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Negative regulation of supramolecular fiber organization →	+0.077	+2.301	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of response to cytokine stimulus →	+0.085	+1.463	<.001	.003	3	10
URINARY_TRACT	Negative regulation of hippocampal neuron apoptotic process →	+1.672	+1.881	<.001	<.001	3	10
LUNG_NSCLC_LUAD	Protein localization to cell junction →	+0.106	+1.718	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,987 associations by consensus.

Small GTPase-mediated signal transduction by PTAFR expression — OESOPHAGUS

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