PSPH

Across TCGA patient cohorts, PSPH RNA expression is significantly associated with the protein abundance of many other proteins, with 13,793 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PSPH-associated proteins across cancer lineages are HSPA14, MCM2, and MCM3. Each is linked with PSPH in more than 6 cancer types. Because this analysis shows association rather than direction, both PSPH-to-partner and partner-to-PSPH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSPH versus HSPA14 in LSCC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PSPH→partner) and Y-score (partner→PSPH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HSPA14 →	+0.350	+0.793	<.001	<.001	3	7
LUAD	MCM2 →	+0.733	+0.868	<.001	<.001	3	7
LUAD	MCM3 →	+0.756	+0.814	<.001	<.001	3	7
LUAD	MCM7 →	+0.774	+0.732	<.001	<.001	3	7
GBM	GTF2I →	+0.460	+1.047	<.001	<.001	3	6
LUAD	ANLN →	+0.685	+0.636	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,793 associations by consensus.

PSPH vs HSPA14 — LSCC

Explore this scatter interactively →