PSORS1C1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PSORS1C1 mutation is significantly associated with the RNA expression of many other genes, with 57 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible PSORS1C1-associated genes across cancer lineages are LINC00440, DEFB129, and MIR874. Each is linked with PSORS1C1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSORS1C1-to-partner and partner-to-PSORS1C1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSORS1C1→partner) and Y-score (partner→PSORS1C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMLINC00440 →+0.073+3.525.001.00232
SKCMDEFB129 →+0.027+4.147<.001.00832
BLCAMIR874 →+0.452+4.266<.001.00332
COADRN7SL25P →+0.236+5.484.002<.00132
UCECRNU6-961P →+0.213+5.738<.001<.00132
UCECRNU6-718P →+0.243+4.555<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

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