PSMD8

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PSMD8 mutation is significantly associated with the total protein of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSMD8-associated genes across cancer lineages are Axl. Each is linked with PSMD8 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSMD8-to-partner and partner-to-PSMD8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Axl grouped by PSMD8-low versus PSMD8-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMD8→partner) and Y-score (partner→PSMD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECAxl →+0.255+2.843.044.03531
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Axl by PSMD8 expression — UCEC

Box plot of Axl in PSMD8-low vs PSMD8-high samples in UCEC.

Explore this box plot interactively →

Exploration