PSMA8

Across TCGA patient cohorts, PSMA8 protein abundance is significantly associated with the RNA expression of many other genes, with 1,998 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PSMA8-associated genes across cancer lineages are TRAFD1, TTC16, and TMIGD2. Each is linked with PSMA8 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSMA8-to-partner and partner-to-PSMA8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSMA8 versus TRAFD1 in LUAD, with a Pearson correlation of 0.77.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMA8→partner) and Y-score (partner→PSMA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TRAFD1 →	+0.876	+0.386	<.001	.001	3	2
LSCC	TTC16 →	+0.389	+0.328	.007	.008	3	2
HNSC	TMIGD2 →	+0.731	+0.527	.004	.004	3	2
LUAD	HLA-DMA →	+1.245	+0.444	.005	.001	3	2
HNSC	RN7SL697P →	-0.523	-0.357	.006	.009	3	2
LSCC	TSPAN32 →	+0.735	+0.534	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,998 associations by consensus.

PSMA8 vs TRAFD1 — LUAD

Explore this scatter interactively →