PSMA8

Across TCGA patient cohorts, PSMA8 protein abundance is significantly associated with the protein abundance of many other proteins, with 3,211 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PSMA8-associated proteins across cancer lineages are PSMA1, PSMA3, and PSMA4. Each is linked with PSMA8 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSMA8-to-partner and partner-to-PSMA8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSMA8 versus PSMA1 in LSCC, with a Pearson correlation of 0.52.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMA8→partner) and Y-score (partner→PSMA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PSMA1 →	+0.230	+0.326	<.001	.003	3	2
BRCA	PSMA3 →	+0.248	+0.306	<.001	<.001	3	2
LSCC	PSMA4 →	+0.229	+0.312	<.001	.001	3	2
BRCA	PSMA6 →	+0.371	+0.455	<.001	<.001	3	2
BRCA	PSMB3 →	+0.300	+0.466	<.001	<.001	3	2
LSCC	TBC1D2B_S155 →	+0.675	+0.420	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,211 associations by consensus.

PSMA8 vs PSMA1 — LSCC

Explore this scatter interactively →