PSMA7

Across TCGA patient cohorts, PSMA7 mutation is significantly associated with the RNA expression of many other genes, with 2,610 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSMA7-associated genes across cancer lineages are MIR147A, RNU6-253P, and HIKESHI. Each is linked with PSMA7 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSMA7-to-partner and partner-to-PSMA7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR147A grouped by PSMA7-low versus PSMA7-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMA7→partner) and Y-score (partner→PSMA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR147A →	+0.426	+5.588	<.001	.004	3	2
BRCA	RNU6-253P →	+0.372	+8.055	<.001	.007	3	2
UCEC	HIKESHI →	+0.572	+3.807	<.001	<.001	3	1
UCEC	SESN3 →	+0.827	+2.721	.007	.003	3	1
UCEC	HYOU1 →	+0.840	+3.475	.001	.002	3	1
UCEC	HIRIP3 →	+0.615	+3.266	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,610 associations by consensus.

MIR147A by PSMA7 expression — BLCA

Explore this box plot interactively →