Q-omics provides the consensus-scored PRYP6 profile across patient tissues and cancer cell-line models. PRYP6 expression is associated with patient survival in 4 of 34 cancer types, with the highest sampling consensus in GBM. Additionally, PRYP6 RNA expression shows 978 significant gene co-expression associations, with the highest sampling consensus in KIRC. Together, these results highlight GBM, and KIRC as cancer lineages where PRYP6 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes PRYP6 survival associations across molecular data types. PRYP6 RNA expression shows survival associations in the most cancer types (4). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

PRYP6 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	4	GBM (36)	view →

This table ranks reproducible PRYP6 RNA expression–survival associations across cancer types. High PRYP6 expression shows unfavorable associations in GBM, THCA, COAD and KIRP. The GBM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify GBM as the clearest survival context for PRYP6 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Tertile	All	0.069	0.415	<.001	36	view →
THCA	OS	Tertile	All	0.277	0.944	<.001	33	view →
COAD	DFS	Tertile	All	0.517	0.791	.006	24	view →
KIRP	OS	Tertile	All	0.599	0.903	.025	9	view →

Pink = unfavorable, green = favorable. all 4 lineages →

PRYP6-GBM (OS)

Kaplan–Meier survival curve for PRYP6 RNA expression in GBM: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with PRYP6 in patient tissues and cancer cell lines. In patient samples, PRYP6 shows the broadest associations at the RNA and protein expression levels, with KIRC recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	978	KIRC (715)	view →
Mutation	64	BRCA (26)	view →