PRYP6

Across TCGA pan-cancer cohorts, PRYP6 RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated PRYP6 data layer.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher PRYP6 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PRYP6 expression acts as an unfavorable survival marker.

GBM, THCA, and COAD are the cancer types where PRYP6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Tertile	All	0.069	0.415	<.001	36	view →
THCA	OS	Tertile	All	0.277	0.944	<.001	33	view →
COAD	DFS	Tertile	All	0.517	0.791	.006	24	view →
KIRP	OS	Tertile	All	0.599	0.903	.025	9	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

PRYP6–GBM (OS)

Open the GBM breakdown →