PRX

Across TCGA patient cohorts, PRX protein abundance is significantly associated with the RNA expression of many other genes, with 3,618 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PRX-associated genes across cancer lineages are TNNC1, LYVE1, and ANKRD1. Each is linked with PRX in more than 2 cancer types. Because this analysis shows association rather than direction, both PRX-to-partner and partner-to-PRX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRX versus TNNC1 in HNSC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRX→partner) and Y-score (partner→PRX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TNNC1 →	+2.496	+0.470	<.001	<.001	3	3
HNSC	LYVE1 →	+1.366	+0.647	<.001	.001	3	3
HNSC	ANKRD1 →	+2.085	+0.586	<.001	<.001	3	3
HNSC	MYL3 →	+0.913	+0.476	<.001	<.001	3	3
HNSC	CCDC141 →	+0.852	+0.730	<.001	<.001	3	3
LSCC	TGFBR2 →	+0.484	+0.289	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,618 associations by consensus.

PRX vs TNNC1 — HNSC

Explore this scatter interactively →