PRSS47

Across TCGA patient cohorts, PRSS47 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,303 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PRSS47-associated GO terms across cancer lineages are Regulation of DNA repair, Positive regulation of post-translational protein modification, and Positive regulation of double-strand break repair via homologous recombination. Each is linked with PRSS47 in more than 13 cancer types. Because this analysis shows association rather than direction, both PRSS47-to-partner and partner-to-PRSS47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA repair grouped by PRSS47-low versus PRSS47-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS47→partner) and Y-score (partner→PRSS47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of DNA repair →	+0.078	+0.071	<.001	<.001	3	14
STAD	Positive regulation of post-translational protein modification →	+0.078	+0.073	<.001	<.001	3	13
ESCA	Positive regulation of double-strand break repair via homologous recombination →	+0.072	+0.117	<.001	.004	3	13
STAD	Positive regulation of DNA repair →	+0.075	+0.080	<.001	<.001	3	13
STAD	Methylation →	+0.071	+0.086	<.001	<.001	3	13
STAD	Regulation of signal transduction by p53 class mediator →	+0.082	+0.068	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,303 associations by consensus.

Regulation of DNA repair by PRSS47 expression — STAD

Explore this box plot interactively →