PRSS37

Across TCGA cell cohorts, PRSS37 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,196 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PRSS37-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Chiasma assembly, and Nuclear-transcribed mRNA poly(A) tail shortening. Each is linked with PRSS37 in more than 5 cancer types. Because this analysis shows association rather than direction, both PRSS37-to-partner and partner-to-PRSS37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by PRSS37-low versus PRSS37-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRSS37→partner) and Y-score (partner→PRSS37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Pre-mRNA catabolic process →	+0.124	+0.049	<.001	.006	2	6
SOFT_TISSUE	Chiasma assembly →	+0.142	+0.020	.002	.007	3	5
LUNG_NSCLC_LUSC	Nuclear-transcribed mRNA poly(A) tail shortening →	+0.096	+0.105	.001	.003	3	5
LUNG_NSCLC_LUAD	Post-transcriptional gene silencing →	+0.051	+0.039	.007	.006	3	5
BLOOD_Myeloma	Organ or tissue specific immune response →	-0.170	-0.052	.001	.004	3	4
BLOOD_Myeloma	Regulation of lysosome size →	-0.081	-0.077	.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,196 associations by consensus.

Pre-mRNA catabolic process by PRSS37 expression — OVARY

Explore this box plot interactively →