PRRC2B

Across TCGA patient cohorts, PRRC2B mutation is significantly associated with the RNA expression of many other genes, with 5,844 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRRC2B-associated genes across cancer lineages are MIR103A1, ERI1, and MRPS11. Each is linked with PRRC2B in more than 4 cancer types. Because this analysis shows association rather than direction, both PRRC2B-to-partner and partner-to-PRRC2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR103A1 grouped by PRRC2B-low versus PRRC2B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRRC2B→partner) and Y-score (partner→PRRC2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR103A1 →	+0.220	+3.498	.001	.002	3	5
COAD	ERI1 →	+0.487	+2.235	.005	.006	3	4
UCEC	MRPS11 →	+0.373	+2.011	<.001	<.001	3	4
UCEC	CHP1 →	+0.436	+1.606	<.001	.002	3	4
UCEC	CNOT7 →	+0.382	+1.987	.001	<.001	3	4
UCEC	KRT8P33 →	+0.378	+2.131	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,844 associations by consensus.

MIR103A1 by PRRC2B expression — COAD

Explore this box plot interactively →