PRR5-ARHGAP8

Across TCGA patient cohorts, PRR5-ARHGAP8 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,629 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PRR5-ARHGAP8-associated proteins across cancer lineages are ZNF830, TCF20, and LIG3. Each is linked with PRR5-ARHGAP8 in more than 4 cancer types. Because this analysis shows association rather than direction, both PRR5-ARHGAP8-to-partner and partner-to-PRR5-ARHGAP8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRR5-ARHGAP8 versus ZNF830 in BRCA, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR5-ARHGAP8→partner) and Y-score (partner→PRR5-ARHGAP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZNF830 →	+0.328	+0.460	.002	.003	3	5
LSCC	TCF20 →	+0.229	+0.337	<.001	<.001	3	4
LSCC	LIG3 →	+0.645	+0.538	<.001	<.001	3	4
COAD	VIPAS39 →	-0.185	-0.287	<.001	.001	3	4
HNSC	SMC1A →	+0.247	+0.591	<.001	<.001	3	4
HNSC	HCFC1 →	+0.182	+0.312	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,629 associations by consensus.

PRR5-ARHGAP8 vs ZNF830 — BRCA

Explore this scatter interactively →