PRR32

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PRR32 mutation is significantly associated with the RNA expression of many other genes, with 1,854 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRR32-associated genes across cancer lineages are RNU6-718P, MIR548AQ, and CPVL-AS1. Each is linked with PRR32 in more than 2 cancer types. Because this analysis shows association rather than direction, both PRR32-to-partner and partner-to-PRR32 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR32→partner) and Y-score (partner→PRR32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU6-718P →+0.107+3.140.004.00433
LIHCMIR548AQ →+0.690+6.676<.001<.00132
LIHCCPVL-AS1 →+0.138+5.758<.001.00332
BRCAOR2T12 →+0.083+5.409<.001.00532
READLINC00265-2P →+0.063+5.653<.001.00332
UCECSPANXN3 →+0.101+2.135<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,854 associations by consensus.

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