PRR15L

Across TCGA patient cohorts, PRR15L mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRR15L-associated genes across cancer lineages are MIR8089, OR52E5, and RNU7-97P. Each is linked with PRR15L in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR15L-to-partner and partner-to-PRR15L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR8089 grouped by PRR15L-low versus PRR15L-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR15L→partner) and Y-score (partner→PRR15L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR8089 →	+0.673	+4.680	<.001	.007	3	1
SKCM	OR52E5 →	+0.061	+4.628	.001	.004	3	1
SKCM	RNU7-97P →	+0.633	+5.075	<.001	.001	3	1
UCEC	MIR6750 →	+0.913	+3.298	<.001	.004	3	1
UCEC	RNA5SP412 →	+1.004	+3.382	<.001	.004	3	1
UCEC	SS18L2P2 →	+0.150	+5.148	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

MIR8089 by PRR15L expression — SKCM

Explore this box plot interactively →