PRR15L

Across TCGA pan-cancer cohorts, PRR15L RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated PRR15L data layer compared with 5 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher PRR15L RNA is associated with better overall survival. In most high-consensus cancer types, elevated PRR15L expression acts as an unfavorable survival marker, although some lineages such as MESO and KIRP show a favorable association.

MESO, KIRP, and STAD are the cancer types where PRR15L RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.674	0.412	<.001	87	view →
KIRP	OS	Tertile	All	0.895	0.674	<.001	70	view →
STAD	OS	Tertile	All	0.656	0.484	.001	62	view →
ACC	DFS	Tertile	All	0.454	0.814	<.001	37	view →
COAD	DFS	Median	IV	0.531	0.223	.014	32	view →
ESCA	OS	Median	All	0.617	1.000	.009	30	view →
HNSC	OS	Tertile	III,IV	0.502	0.304	.006	27	view →
KIRC	OS	Tertile	All	0.915	0.791	<.001	25	view →
THCA	DFS	Median	II,III,IV	0.872	0.646	.010	23	view →
UCEC	DFS	Tertile	III,IV	0.704	0.378	.013	12	view →
LGG	DFS	Quartile	All	0.656	0.782	.014	11	view →
BRCA	OS	Median	IV	0.768	0.319	.001	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

PRR15L–MESO (OS)

Open the MESO breakdown →