PRMT5-AS1

Across TCGA patient cohorts, PRMT5-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,780 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRMT5-AS1-associated proteins across cancer lineages are SUPT16H, UTP4, and VRK1. Each is linked with PRMT5-AS1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PRMT5-AS1-to-partner and partner-to-PRMT5-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRMT5-AS1 versus SUPT16H in GBM, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRMT5-AS1→partner) and Y-score (partner→PRMT5-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SUPT16H →	+0.471	+0.202	<.001	<.001	3	8
LSCC	UTP4 →	+0.264	+0.161	<.001	<.001	3	5
LSCC	VRK1 →	+0.559	+0.240	<.001	<.001	3	5
LSCC	AFF4 →	+0.249	+0.196	<.001	<.001	3	5
LSCC	GTF3C2 →	+0.234	+0.155	<.001	<.001	3	5
GBM	GTF3C4 →	+0.326	+0.284	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,780 associations by consensus.

PRMT5-AS1 vs SUPT16H — GBM

Explore this scatter interactively →