PRLHR

Across TCGA cell cohorts, PRLHR mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PRLHR-associated genes across cancer lineages are TFDP3, C14orf180, and CENPVL1. Each is linked with PRLHR in more than 1 cancer types. Because this analysis shows association rather than direction, both PRLHR-to-partner and partner-to-PRLHR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFDP3 grouped by PRLHR-low versus PRLHR-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRLHR→partner) and Y-score (partner→PRLHR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TFDP3 →	+0.033	+4.518	<.001	<.001	3	1
LARGE_INTESTINE	C14orf180 →	+0.101	+3.155	.003	.008	3	1
LARGE_INTESTINE	CENPVL1 →	+0.150	+3.510	<.001	.003	3	1
LARGE_INTESTINE	NEXMIF →	+0.281	+3.196	<.001	.007	3	1
LARGE_INTESTINE	F11 →	+0.054	+3.882	<.001	.001	3	1
BLOOD_Leukemia	VSX2 →	+0.024	+3.258	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

TFDP3 by PRLHR expression — LARGE_INTESTINE

Explore this box plot interactively →