PRLHR

Across TCGA pan-cancer cohorts, PRLHR RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated PRLHR data layer compared with 7 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher PRLHR RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PRLHR expression acts as an unfavorable survival marker, although some lineages such as LGG and UCEC show a favorable association.

COAD, LGG, and UCEC are the cancer types where PRLHR RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Quartile	II,III,IV	0.654	0.823	<.001	97	view →
LGG	DFS	Median	All	0.834	0.639	<.001	54	view →
UCEC	DFS	Tertile	III,IV	0.744	0.479	.010	40	view →
BLCA	OS	Tertile	IV	0.129	0.339	.004	38	view →
CESC	OS	Tertile	II,III,IV	0.894	0.696	.017	36	view →
BRCA	DFS	Tertile	All	0.570	1.000	.033	36	view →
SKCM	OS	Tertile	All	0.703	0.801	.017	33	view →
CHOL	DFS	Tertile	All	0.842	0.222	<.001	29	view →
KIRP	OS	Tertile	All	0.436	0.790	.002	21	view →
ACC	DFS	Tertile	III,IV	0.247	0.639	.017	18	view →
LUAD	DFS	Tertile	IV	0.240	0.625	.030	18	view →
MESO	OS	Tertile	All	0.316	0.679	.017	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

PRLHR–COAD (OS)

Open the COAD breakdown →