PRKCG

Across TCGA cell cohorts, PRKCG RNA expression is significantly associated with the go_rna of many other GO terms, with 3,109 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PRKCG-associated GO terms across cancer lineages are Positive regulation of mismatch repair, Regulation of mismatch repair, and Sensory organ morphogenesis. Each is linked with PRKCG in more than 9 cancer types. Because this analysis shows association rather than direction, both PRKCG-to-partner and partner-to-PRKCG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mismatch repair grouped by PRKCG-low versus PRKCG-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKCG→partner) and Y-score (partner→PRKCG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of mismatch repair →	-0.143	-1.240	<.001	<.001	3	10
LUNG_NSCLC_LUAD	Regulation of mismatch repair →	-0.157	-0.525	<.001	.003	3	9
BONE	Sensory organ morphogenesis →	-0.048	-1.182	<.001	<.001	2	9
BONE	ATP synthesis coupled electron transport →	+0.074	+0.732	<.001	<.001	3	8
BONE	Mitochondrial ATP synthesis coupled electron transport →	+0.074	+0.732	<.001	<.001	3	8
SOFT_TISSUE	Negative regulation of receptor-mediated endocytosis →	+0.092	+1.087	<.001	.009	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,109 associations by consensus.

Positive regulation of mismatch repair by PRKCG expression — STOMACH

Explore this box plot interactively →