PRKCG

Across TCGA pan-cancer cohorts, PRKCG RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated PRKCG data layer compared with 9 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher PRKCG RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PRKCG expression acts as an unfavorable survival marker, although some lineages such as SKCM and SCLC show a favorable association.

KIRC, SKCM, and SCLC are the cancer types where PRKCG RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.544	0.715	<.001	166	view →
SKCM	OS	Tertile	II,III,IV	0.535	0.301	<.001	91	view →
SCLC	DFS	Median	II,III,IV	0.638	0.280	<.001	90	view →
ACC	DFS	Tertile	All	0.298	0.748	<.001	74	view →
READ	OS	Quartile	III,IV	0.865	0.466	.001	34	view →
THYM	OS	Median	All	1.000	0.701	<.001	19	view →
PCPG	DFS	Tertile	All	0.490	0.941	<.001	18	view →
LAML	DFS	Median	All	0.202	0.560	<.001	14	view →
UCEC	OS	Median	IV	0.251	0.651	.011	12	view →
ESCA	OS	Tertile	All	0.436	1.000	.011	12	view →
LUAD	DFS	Median	III,IV	0.336	0.631	.006	11	view →
LIHC	OS	Median	All	0.692	0.817	.015	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

PRKCG–KIRC (OS)

Open the KIRC breakdown →