PRKAG2-AS1

Across TCGA patient cohorts, PRKAG2-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,117 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PRKAG2-AS1-associated proteins across cancer lineages are PRKAG2_S122, PRKAG2_S71, and PRKAR2B. Each is linked with PRKAG2-AS1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PRKAG2-AS1-to-partner and partner-to-PRKAG2-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRKAG2-AS1 versus PRKAG2_S122 in UCEC, with a Pearson correlation of 0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKAG2-AS1→partner) and Y-score (partner→PRKAG2-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRKAG2_S122 →	+0.733	+1.239	<.001	<.001	3	8
BRCA	PRKAG2_S71 →	+0.614	+0.864	<.001	<.001	3	8
GBM	PRKAR2B →	+0.640	+0.675	<.001	<.001	3	6
LSCC	JUNB →	-0.346	-0.486	.008	.005	3	5
HNSC	PRKAG2_S196 →	+0.567	+0.576	<.001	.001	3	4
BRCA	DDAH1 →	+0.687	+0.943	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,117 associations by consensus.

PRKAG2-AS1 vs PRKAG2_S122 — UCEC

Explore this scatter interactively →