PRKAG2-AS1

Across TCGA pan-cancer cohorts, PRKAG2-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated PRKAG2-AS1 data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher PRKAG2-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated PRKAG2-AS1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and BRCA show a favorable association.

PAAD, BRCA, and ACC are the cancer types where PRKAG2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Quartile	All	0.549	0.256	<.001	49	view →
BRCA	OS	Median	All	0.945	0.899	.001	37	view →
ACC	DFS	Tertile	II,III,IV	0.222	0.758	<.001	37	view →
GBM	DFS	Median	All	0.156	0.249	.001	30	view →
UVM	DFS	Median	III,IV	0.171	0.831	.001	29	view →
STAD	OS	Tertile	III,IV	0.229	0.615	.013	27	view →
LUAD	OS	Tertile	All	0.831	0.741	.015	21	view →
PRAD	DFS	Tertile	All	0.701	0.894	.001	18	view →
LAML	DFS	Median	All	0.289	0.463	.013	16	view →
SKCM	OS	Quartile	III,IV	0.614	0.933	.002	15	view →
UCEC	OS	Quartile	IV	0.396	0.779	.011	12	view →
UCS	OS	Tertile	IV	0.828	0.387	.024	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

PRKAG2-AS1–PAAD (OS)

Open the PAAD breakdown →