PRKAA1

Across TCGA patient cohorts, PRKAA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,200 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PRKAA1-associated proteins across cancer lineages are PAIP1, TRIOBP, and UBE2J1. Each is linked with PRKAA1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PRKAA1-to-partner and partner-to-PRKAA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRKAA1 versus PAIP1 in LSCC, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKAA1→partner) and Y-score (partner→PRKAA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PAIP1 →	+0.316	+0.541	<.001	<.001	3	4
BRCA	TRIOBP →	+0.361	+0.739	<.001	<.001	3	3
LUAD	UBE2J1 →	-0.343	-0.443	.008	<.001	3	3
LUAD	WDR70 →	+0.283	+0.479	<.001	<.001	3	3
LSCC	SPCS3 →	-0.443	-0.333	<.001	.006	3	3
LSCC	SRP54 →	-0.179	-0.419	.003	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,200 associations by consensus.

PRKAA1 vs PAIP1 — LSCC

Explore this scatter interactively →