PRICKLE3

Across TCGA patient cohorts, PRICKLE3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,716 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRICKLE3-associated proteins across cancer lineages are PCYT1A, PUS7, and KIF13B. Each is linked with PRICKLE3 in more than 3 cancer types. Because this analysis shows association rather than direction, both PRICKLE3-to-partner and partner-to-PRICKLE3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRICKLE3 versus PCYT1A in LSCC, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRICKLE3→partner) and Y-score (partner→PRICKLE3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PCYT1A →	+0.521	+0.560	<.001	<.001	3	4
LUAD	PUS7 →	+0.254	+0.292	.004	.006	3	4
HNSC	KIF13B →	-0.440	-0.714	<.001	<.001	3	4
LUAD	TBC1D2B_S155 →	-0.367	-0.491	<.001	<.001	3	4
LUAD	KIF13B_S1689 →	-0.559	-0.307	<.001	<.001	3	4
LSCC	SRSF9 →	+0.281	+0.416	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,716 associations by consensus.

PRICKLE3 vs PCYT1A — LSCC

Explore this scatter interactively →