PRICKLE2-DT

Across TCGA patient cohorts, PRICKLE2-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 9,292 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PRICKLE2-DT-associated proteins across cancer lineages are CNN2, LOXL2, and MRC2. Each is linked with PRICKLE2-DT in more than 6 cancer types. Because this analysis shows association rather than direction, both PRICKLE2-DT-to-partner and partner-to-PRICKLE2-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRICKLE2-DT versus CNN2 in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRICKLE2-DT→partner) and Y-score (partner→PRICKLE2-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CNN2 →	+0.820	+0.449	<.001	<.001	3	7
LSCC	LOXL2 →	+0.787	+0.102	<.001	<.001	3	7
BRCA	MRC2 →	+0.701	+0.268	<.001	<.001	3	6
OV	MXRA5 →	+0.942	+0.421	<.001	<.001	3	6
BRCA	NXN →	+0.573	+0.207	<.001	<.001	3	6
OV	RAB31 →	+0.727	+0.441	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,292 associations by consensus.

PRICKLE2-DT vs CNN2 — OV

Explore this scatter interactively →