PRDM12

Across TCGA patient cohorts, PRDM12 protein abundance is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PRDM12-associated genes across cancer lineages are KCNK15, RN7SL145P, and CXCR6. Each is linked with PRDM12 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRDM12-to-partner and partner-to-PRDM12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRDM12 versus KCNK15 in CCRCC, with a Pearson correlation of -0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDM12→partner) and Y-score (partner→PRDM12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	KCNK15 →	-0.820	-0.556	.006	.001	3	1
CCRCC	RN7SL145P →	+0.470	+0.556	.009	.001	3	1
CCRCC	CXCR6 →	+0.458	+0.519	.006	.007	2	1
CCRCC	LINC02139 →	+0.163	+0.556	.008	.001	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

PRDM12 vs KCNK15 — CCRCC

Explore this scatter interactively →